Found a better way and more useful for my R9 3950X+2080Ti Im able to run Folding@Home (full) CPU/GPU and playing ETS2 under current condition without any impact on the game performance .
If I don't look at the CPU/GPU stats I wouldn't even know I actually Fold the same time I drive though the virtual world of Europe . What I did though, dont know if really necessary I set Affinity for Folding to 24Cores leaving 8 for what ever rest it can be used in this case ETS2 .
I then took aprox 3500 km route and I didn't feel any difference or any major hiccups , its a good way to have fun and fight Covid19 at the same time I guess .
When I setup for that test I dint actually thought it will work smoothly , I thought there will be some huge frame drops , or sort of stuttering and slowdowns but surprisingly it runs amazingly good.
I'm guessing Folding@home uses the Cuda cores which have no use in ETS2 and obviously the 8 cores from the CPU are sufficient enough to run the game without really impacting the game performance .
Thanks guys for all the help and advises